45+ contains a small amount of inulin which is a high FODMAP food and psyllium husk which some people find may cause irritation in the gut. It is recommended 45+ Smoothie is avoided during the elimination phase of the FODMAP diet.

The use of 45+ however, could be discussed with a healthcare practitioner for use during the re-challenge phase as the small amount of inulin may be tolerable during the re-challenge and maintenance phases of the low FODMAP diet for some people.